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| Product Name | AICDA, 1-198aa, Human, His tag, E Coli (Denatured) |
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| Description | MW: 26.1kDa (218aa). Purity >85% by SDS-PAGE. AICDA, also known as AID, is involved in somatic hypermutation, gene conversion, and class-switch recombination in B-lymphocytes. This protein is required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. It may also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. Recombinant human AICDA protein, fused to His-tag at N-terminus, was expressed in E |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Activation-induced cytidine deaminase; AID; ARP2; CDA2; HIGM2] |
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| Gene, Accession, CAS # | AICDA, Gene ID: 57379, Accession: NP_065712 |
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| Catalog # | MBS205181 |
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| Order / More Info | AICDA, 1-198aa, Human, His tag, E Coli (Denatured) from MYBIOSOURCE INC. |
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| Product Specific References | Guo J.u., et al. (2010) Cell. 145:423-434; Noguchi E., et al. (2001) J. Allergy Clin. 108:382-386 |
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