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| Product Name | GCLM, 1-274aa, Human, His tag, E Coli |
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| Description | MW: 33.3kDa (298aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Recombinant human GCLM protein, fused to His-tag at N-terminus, was expressed in E Coli and purifie |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Glutamate-cysteine ligase modifier subunit; Glutamate-cysteine ligase; modifier subunit; GLCLR] |
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| Gene, Accession, CAS # | GCLM, Gene ID: 2730, Accession: NP_002052 |
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| Catalog # | MBS204385 |
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| Order / More Info | GCLM, 1-274aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Hanzawa,R., et al. (2011) Psychiatry Clin. Neurosci. 65 (1), 39-46 |
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