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| Product Name | AMPK, ACC, Antibody Sampler Kit, BioAssay™ |
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| Description | Purified by Protein A and peptide affinity chromatography. The AMPK and ACC Antibody Sampler Kit provides an economical means to investigate energy homeostasis and fatty acid synthesis within the cell. The kit contains primary and secondary antibodies to perform four Western mini-blots with each antibody. Background: AMP-activated protein kinase (AMPK) is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis (1). AMPK is a heterotrimeric complex composed of a catalytic subunit and regulatory and subunits, each of which is encoded by two or three distinct genes ( 1, 2; 1, 2; 1, 2, 3)(2). The kinase is activated by an elevated AMP/ATP ratio due to cellular and environmental stress, such as heat shock, hypoxia and ischemia (1). The tumor suppressor LKB1, in association with accessory proteins STRAD and MO25, phosphorylates AMPK at Thr172 in the activation loop and this phosphorylation is required for AMPK activation (3-5). AMPK is a |
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| Size | 1 kit |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | A1475-25 |
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| Order / More Info | AMPK, ACC, Antibody Sampler Kit, BioAssay™ from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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