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| Product Name | AMPK Activator V, Ampkinone (AKN, AMPK Signaling Activator V) |
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| Description | Purity ~98% (HPLC). A cell-permeable benzopyran compound that stimulates both LKB1 and CaMKK-mediated AMPK activity indirectly with no noticeable effect on purified AMPK, cellular AMP/ATP ratio, PI 3-K/Akt signaling and respiratory chain, and displays antidiabetic and antiobesity properties. Shown to induce phosphorylation of AMPK-Thr172 and ACC-Ser79 in L6 cells (EC50 = 4.3uM), C2C12 myocytes, 3T3-L1 preadipocytes and HepG2 hepatic cells, and enhance glucose uptake and insulin sensitivity in high fat-diet-induced obesity mouse model (10mg/kg, s.c.) with the lowering of cholesterol and nonesterified fatty acids. Formula: C31H23NO6 Molecular Weight: 505.5 Solubility: DMSO (25mg/ml) |
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| Size | 5mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217176 |
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| Order / More Info | AMPK Activator V, Ampkinone (AKN, AMPK Signaling Activator V) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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