| 产品详情 |
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| Product Name | Glutathione, Reduced/Oxidized (GSH/GSSG) Detection BioAssay™ Kit |
| Description | Improved GSH/GSSG Assay available in G8124-10 Microplate and G8124-11 Cuvette Formats (96 assays) Reduced glutathione (GSH) is a tripipeptide (gamma-glutamylcyteinylglycine) that contains a free thiol group. GSH is a major tissue antioxidant that provides reducing equivalents for the glutathione peroxidase (GPx) catalyzed reduction of lipid hydroperoxides to their corresponding alcohols and hydrogen peroxide to water: GPx H2O2 + 2GSH -------------> GSSG + 2H2O In the GPx catalyzed reaction, the formation of a disulfide bond between two GSH molecules gives rise to oxidized glutathione (GSSG). The enzyme glutathione reductase (GR) recycles GSSG to GSH with the simultaneous oxidation of beta-nicotinamide adenine dinucleotide phosphate (b-NADPH2): GR GSSG + NADPH -------------> 2GSH + NADP+ When cells are exposed to increased levels of oxidative stress, GSSG will accumulate and the ratio of GSH to GSSG will decrease. Therefore, the determination of the GSH/GSSG ratio and the quantification |
| Size | 1 kit |
| Concentration | n/a |
| Applications | n/a |
| Other Names | n/a |
| Gene, Accession, CAS # | n/a |
| Catalog # | G8124-10 |
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| Order / More Info | Glutathione, Reduced/Oxidized (GSH/GSSG) Detection BioAssay™ Kit from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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