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| Product Name | Glutathione Reductase, Colorimetric Kit, BioAssay™ |
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| Description | Glutathione reductase (GR, EC 1.6.4.2) is a ubiquitous enzyme, which catalyzes the reduction of oxidized glutathione (GSSG) to glutathione (GSH). Glutathione reductase is essential for the glutathione redox cycle that maintains adequate levels of reduced cellular GSH. GSH serves as an antioxidant, reacting with free radicals and organic peroxides, in amino acid transport, and as a substrate for the glutathione peroxidases and glutathione Stransferases in the detoxification of organic peroxides and metabolism of xenobiotics, respectively.1 This homodimeric enzyme is a member of the family of flavoprotein disulfide oxidoreductases. Each subunit has four domains; beginning at the N-terminus: an FAD-binding domain, an NADPH-binding domain, a central domain, and an interface domain. The active site of GR is at the dimeric interface. Since the GSSG binding site is composed of residues from both subunits, only the dimeric form is active.2 Glutathione Reductase GSSG + NADPH + H+ -------------- |
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| Size | 1 kit |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | G8127-20 |
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| Price | |
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| Order / More Info | Glutathione Reductase, Colorimetric Kit, BioAssay™ from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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