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| Product Name | KAE1, Recombinant, Saccharomyces Cerevisiae, aa1-386, His-tag |
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| Description | Purity ~90% (SDS-PAGE). KAE1, Recombinant, Saccharomyces Cerevisiae, aa1-386, His-Tag (Probable tRNA threonylcarbamoyladenosine biosynthesis Protein KAE1). Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. Source: Recombinant protein corresponding to aa1-386 from saccharomyces cerevisiae KAE1, fused to His-Tag at N-terminal expressed in E. coli. Molecular Weight: ~46.7kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Kinase-associated endopeptidase 1 N6-L-threonylcarbamoyladenine synthase, t(6)A synthase t(6)A37 threonylcarbamoyladenosine biosynthesis protein, KAE1 tRNA threonylcarbamoyladenosine biosynthesis protein KAE1 |
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| Gene, Accession, CAS # | SwissProt: P36132 |
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| Catalog # | 373894 |
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| Order / More Info | KAE1, Recombinant, Saccharomyces Cerevisiae, aa1-386, His-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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