| 产品名称 |
BD1, Recombinant, Human (Beta-Defensin 1, BD-1, Defensin, beta 1, DEFB1, HBD1) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | BD1, Recombinant, Human (Beta-Defensin 1, BD-1, Defensin, beta 1, DEFB1, HBD1) |
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| Description | Purity ~98% (SDS-PAGE). The Defensin family are highly similar in their protein sequence and are microbicidal and cytotoxic peptides made by neutrophils. Beta Defensin-1 (BD-1) is an antimicrobial peptide having the resistance of epithelial surfaces to microbial colonization. BD-1 has close proximity to Defensin alpha-1 and has been implicated in the pathogenesis of cystic fibrosis. Skin of patients having atopic dermatitis patients and mycosis fungoides (non-lesional and lesional) show lower human BD-1 mRNA expression and higher human BD-2 and human BD-3 mRNA expression. Beta Defensin is highly expressed by epithelial cells. BD-1 may play a role in the pathogenesis of severe sepsis. Variation in human BD-1 contributes to asthma diagnosis, with apparent gender- specific effects. Human BD-3 is a dimer, while human BD-1 and human BD-2 are monomeric. Source: Recombinant protein corresponding to human Beta Defensin, a single, non-glycosylated polypeptide chain containing 47aa, expressed in |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | BD-1, BD1, BD 1 |
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| Gene, Accession, CAS # | DEFB1, Gene ID: 1672, SwissProt: P60022 |
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| Catalog # | 219452 |
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| Order / More Info | BD1, Recombinant, Human (Beta-Defensin 1, BD-1, Defensin, beta 1, DEFB1, HBD1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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