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| Product Name | BD-4, Recombinant, Human (Beta-defensin 104, BEFB4) |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. Defensins (alpha and beta)are cationic peptides with a broad spectrum of antimicrobial activity thatcomprise an important arm of the innate immune system. The alpha-defensins aredistinguished from the beta-defensins by the pairing of their three disulfidebonds. To date, six human beta-defensins have been identified BD-1, BD-2, BD-3,BD-4, BD-5 and BD-6. beta-defensins are expressed on some leukocytes and atepithelial surfaces.nbsp In addition totheir direct antimicrobial activities, they can act as chemoattractants towardsimmature dendritic cells and memory T cells.nbspThe beta-defensin proteins are expressed as the C-terminal portion of precursorsand are released by proteolytic cleavage of a signal sequence and in somecases, a propeptide sequence. beta-defensins contain a six-cysteine motif thatforms three intra-molecular disulfide bonds.nbspnbspBD-4 is expressed intestis, stomach, uterus, neutrophils, thyroid, lung and kidney.nbsp In addi |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143289 |
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| Order / More Info | BD-4, Recombinant, Human (Beta-defensin 104, BEFB4) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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