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| Product Name | DPMQ 2 HCl |
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| Description | MW: 339.2. Purity 99% (TLC); NMR (Conforms). PDGFRbeta inhibitorPotent and selective inhibitor of glycogen synthase kinase-3beta (GSK3beta, IC50 = 5 nM) and GSK3alpha (IC50 = 10 nM)1. Induces osteoblastogenesis, increases mineralization and inhibits adipogenesis in ST2 cells2. Promotes replication and survival of pancreatic beta cells3. Enhances differentiation and reduces proliferation of adult human olfactory epithelium neural precursors4. Cell permeable and active in vivo.Scien |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [CHIR-99021; 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile; 5,7-Dimethoxy-3-(4-pyridinyl) quinoline dihydrochloride] |
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| Gene, Accession, CAS # | CAS: 137206-97-4 |
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| Catalog # | MBS515080 |
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| Order / More Info | DPMQ 2 HCl from MYBIOSOURCE INC. |
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| Product Specific References | 1. CN Bennett et al. J. Biol. Chem. 2002 277:30998 2. CN Bennett et al. PNAS 2005 102:3324 3. R Mussmann et al. J. Biol. Chem. 2007 282:12030 4. AP Manceur et al. Exp. Cell. Res. 2011 317:2086 |
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