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| Product Name | Cytochalasin A |
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| Description | Purity >98%. The cytochalasins are cell-permeable fungal metabolites which inhibit actin polymerization. This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion. Cytochalasin A is an oxidized analog of cytochalasin B which uniquely inhibits HIV-1 protease (IC50 = 3 µM). Cytochalasins A and B differ from other cytochalasins in being able to rapidly and reversibly inhibit glucose transport by competitively binding glucose transporters (Ki = 4.0 and 0.6 µM, respectively).11 Cytochalasin A also induces the phosphorylation of the tyrosine phosphatase PTP3 of Dictyostelium, activating STATc.12 |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (3E,9R,11E,12aS,13S,15S,15aS,16S,18aS)-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-13-hydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-2H-oxacyclotetradecino[2,3-d]isoindole-2,5,18-trione, Dehydrophomin, NSC 174119, Phomin |
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| Gene, Accession, CAS # | CAS: 14110-64-6 |
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| Catalog # | LS-H7320 |
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| Order / More Info | Cytochalasin A from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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