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| Product Name | SRGAP3-BRAF (Sex12Bex9), Active |
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| Description | 1-513 exon12 (SRGAP3) 381-end or exon9-18 (BRAF). MW: ~128 kDa. Description: Recombinant human fusion SRGAP3 (1-513 exon12)-BRAF (381-end or exon9-18) protein was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: KIAA1549-BRAF is a gene fusion resulting from a tandem duplication event involving the BRAF kinase gene that have recently been identified as the most frequent genetic alteration in many cancers. The KIAA1549-BRAF fusion typically result |
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| Size | 0.005 mg, 0.01 mg |
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| Concentration | n/a |
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| Applications | Kinase Assay |
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| Other Names | [Homo sapiens SLIT-ROBO Rho GTPase activating protein 3 (SRGAP3), transcript variant 1, mRNA; SLIT-ROBO Rho GTPase-activating protein 3; SLIT-ROBO Rho GTPase-activating protein 3; SLIT-ROBO Rho GTPase activating protein 3; Mental disorder-associated GAP; Rho GTPase-activating protein 14; WAVE-associated Rac GTPase-activating protein; WRP] |
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| Gene, Accession, CAS # | SRGAP3-BRAF, Gene ID: 9901, Accession: NM_014850.3 |
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| Catalog # | MBS515459 |
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| Order / More Info | SRGAP3-BRAF (Sex12Bex9), Active from MYBIOSOURCE INC. |
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| Product Specific References | 1. Dougherty, M J. et al: Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas. Neuro Oncol. 2010 Jul;12 (7):621-30. 2. Badiali, M. et al: KIAA1549-BRAF fusions and IDH mutations can coexist in diffuse gliomas of adults. Brain Pathol. 2012 Nov;22 (6):841-7. |
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