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| Product Name | HIV-1 pol Integrase, Recombinant (Human Immunodeficiency Virus-1) |
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| Description | Purity ≥95% by HPLC and SDS-PAGE. Integrase is an enzyme produced by the HIV which enables its genetic material to be integrated into the DNA of the infected cell and is a key component in the pre-integration complex. HIV integrase contains 3 domains, an N-terminal HH-CC zinc fingerdomainwhich is partially responsible for multimerization, a central catalytic domain and a C-terminal domain. Both Central catalytic domain and C-terminal domains have been shown to bind both viral and cellular DNA. No crystal structure data exists with Integrase bound to its DNA substrates. HIV-1 integrase functions as a dimeror a tetramer. Additionally, several host cellular proteins interact with integrase and may facilitate the integration process. Description: The E.coli derived 26kD recombinant protein is a non-glycosylated polypeptide chain, containing the HIV-1 immunodominant regions from the pol protein (intergrase) and fused with six histidines at the N-terminus. Applications: Suitable for use as a |
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| Size | 100ug, 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | H6003-15C |
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| Order / More Info | HIV-1 pol Integrase, Recombinant (Human Immunodeficiency Virus-1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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