| 产品详情 |
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| Product Name | PLK1, GST-Tag, Recombinant (PLK, STPK13, Serine/Threonine-Protein Kinase PLK1) |
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| Description | Lysate. Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of APC/C inhibitors, and the regulation of mitotic exit and cytokinesis. Required for recovery after DNA damage checkpoint and entry into mitosis. Required for kinetochore localization of BUB1B. Phosphorylates SGOL1. Required for spindle pole localization of isoform 3 of SGOL1 and plays a role in regulating its centriole cohesion function. Phosphorylates BORA, and thereby promotes the degradation of BORA. Contributes to the regulation of AURKA function. Regulates TP53 stability through phosphorylation of TOPORS. Source: Partial length protein corresponding to of PLK1, fused to GST-Tag at N-terminal, expressed in E. coli. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be |
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| Size | 200ug |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | PLK1, Gene ID: 5347, Accession: NP_005021, SwissProt: P53350 |
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| Catalog # | 500894 |
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| Order / More Info | PLK1, GST-Tag, Recombinant (PLK, STPK13, Serine/Threonine-Protein Kinase PLK1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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