| 产品详情 |
| Edit |   |
|---|
| Product Name | 24-dehydro Cholesterol |
|---|
| Description | Purity >98%. 24-dehydro Cholesterol is an immediate precursor to cholesterol in the Bloch pathway of cholesterol biosynthesis. Structurally, it varies from cholesterol only by a single double bond at carbon 24 and has been used as cholesterol substitute in cellular membrane studies. During brain development, 24-dehydro cholesterol transiently accumulates, composing up to 30% of total brain sterol, where it is poised to rapidly enrich membrane sterols. However, defects in cholesterol synthesis can lead to a condition called, desmosterolosis, which results in an accumulation of excess 24-dehydro cholesterol. 24-dehydro Cholesterol has been reported to activate liver X receptor-target genes in both the liver of cholesterol-free mice and in cholesterol-starved macrophage foam cells in atherosclerotic lesions. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | (3Beta)-cholesta-5,24-dien-3-ol, Desmosterol, NSC 226126 |
|---|
| Gene, Accession, CAS # | CAS: 313-04-2 |
|---|
| Catalog # | LS-H5967 |
|---|
| Price | |
|---|
| Order / More Info | 24-dehydro Cholesterol from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|