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| Product Name | Recombinant Human Pro-neuregulin-2, membrane-bound isoform |
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| Description | 112-405. Partial, provide the Extracellular Domain. MW: 48.76kD. Purity >90% as determined by SDS-PAGE. Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. May also promote the heterodimerization with the EGF receptor. |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.1 mg (E-Coli), 0.1 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Divergent of neuregulin-1; DON-1; Neural- and thymus-derived activator for ERBB kinases; NTAK] |
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| Gene, Accession, CAS # | NRG2, Gene ID: 9542, Accession: NP_001171864.1 |
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| Catalog # | MBS1164697 |
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| Order / More Info | Recombinant Human Pro-neuregulin-2, membrane-bound isoform from MYBIOSOURCE INC. |
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| Product Specific References | A novel brain-derived member of the epidermal growth factor family that interacts with ErbB3 and ErbB4.Higashiyama S., Horikawa M., Yamada K., Ichino N., Nakano N., Nakagawa T., Miyagawa J., Matsushita N., Nagatsu T., Taniguchi N., Ishiguro H.J. Biochem. 122:675-680(1997) Characterization of a neuregulin-related gene, Don-1, that is highly expressed in restricted regions of the cerebellum and hippocampus.Busfield S.J., Michnick D.A., Chickering T.W., Revett T.L., Ma J., Woolf E.A., Comrack C.A., |
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