| 产品详情 |
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| Product Name | Recombinant Human Prostaglandin G/H synthase 2 |
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| Description | 18-601aa; Partial. MW: 70.9kD. Purity >90% as determined by SDS-PAGE. Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2 ] |
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| Gene, Accession, CAS # | PTGS2, Gene ID: 5743, Accession: NP_000954.1 |
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| Catalog # | MBS948707 |
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| Order / More Info | Recombinant Human Prostaglandin G/H synthase 2 from MYBIOSOURCE INC. |
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| Product Specific References | Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines.Jones D.A., Carlton D.P., McIntyre T.M., Zimmerman G.A., Prescott S.M.J. Biol. Chem. 268:9049-9054(1993) Human cyclooxygenase-2 cDNA.Hla T., Neilson K.Proc. Natl. Acad. Sci. U.S.A. 89:7384-7388(1992) Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2.Kosaka T., Miyata A., Ihara H., Hara S., Sugimoto T., Takeda O., Takahashi E., Tan |
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