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| Product Name | Recombinant Human Proteasome activator complex subunit 3 protein |
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| Description | 2-252aa; Partial. MW: 56.5kD. Purity >90% as determined by SDS-PAGE. Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [11S regulator complex subunit gamma; REG-gamma; Activator of multicatalytic protease subunit 3Ki nuclear autoantigen; Proteasome activator 28 subunit gamma; PA28g; PA28gamma] |
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| Gene, Accession, CAS # | PSME3, Gene ID: 10197, Accession: NP_005780.2 |
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| Catalog # | MBS1265287 |
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| Order / More Info | Recombinant Human Proteasome activator complex subunit 3 protein from MYBIOSOURCE INC. |
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| Product Specific References | Cloning and nucleotide sequence of cDNA for Ki antigen, a highly conserved nuclear protein detected with sera from patients with systemic lupus erythematosus.Nikaido T., Shimada K., Shibata M., Hata M., Sakamoto M., Takasaki Y., Sato C., Takahashi T., Nishida Y.Clin. Exp. Immunol. 79:209-214(1990) |
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