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| Product Name | BUB1B, Active |
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| Description | 613-end. MW: ~73 kDa. Description: Recombinant human BUB1B (613-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: BUB1B or budding uninhibited by benzimidazoles 1 homolog beta is involved in spindle checkpoint function and has been localized to the kinetochore. BUB1B plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation (1). BUB1B link |
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| Size | 0.005 mg, 0.01 mg |
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| Concentration | n/a |
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| Applications | Kinase Assay, Western Blot (WB) |
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| Other Names | [Homo sapiens BUB1 mitotic checkpoint serine/threonine kinase B (BUB1B), mRNA; Mitotic checkpoint serine/threonine-protein kinase BUB1 beta; mitotic checkpoint serine/threonine-protein kinase BUB1 beta; BUB1 mitotic checkpoint serine/threonine kinase B; MAD3/BUB1-related protein kinase; hBUBR1; Mitotic checkpoint kinase MAD3L; Protein SSK1] |
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| Gene, Accession, CAS # | BUB1B, Gene ID: 701, Accession: NM_001211.5 |
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| Catalog # | MBS515461 |
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| Order / More Info | BUB1B, Active from MYBIOSOURCE INC. |
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| Product Specific References | 1. Rio Frio. Et.al: Homozygous BUB1B mutation and susceptibility to gastrointestinal neoplasia. New Eng. J. Med. 363: 2628-2637, 2010. 2. Lampson, M. A., Kapoor. et.al: The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachments. Nature Cell Biol. 7: 93-98, 2005. |
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