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| Product Name | HFE Protein, Rat Control Peptide (HLA-H) |
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| Description | Highly purified. An 18-aa peptide sequence within the C-terminus of rat HFE. Elemental iron is required for a variety of normal cellular functions and vital for proper growth and development. However, natural iron is quite insoluble and excess iron is harmful, since it can catalyze the formation of potentially damaging reactive oxygen species. Humans also have very limited capacity to excrete iron. Therefore, cells have developed mechanisms to improve solubility of iron and to control intracellular iron levels at the point of absorption in the intestine and other tissue. Several proteins including Ferritin, transferrin (Tf), transferrin receptors (TfRs), and iron regulatory proteins (IRPs), iron transporter (NRMAP2/DMT1/DCT1) etc play a key role in iron metabolism. Some genes involved in iron-metabolism are associated with genetic disorders such as Friedreich's Ataxia (Frataxin), genetic hemochromatosis (HFE), and Sex-linked anemia (Hephaestin). Hereditary hemochromatosis (HHC) is most |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | H2500 |
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| Order / More Info | HFE Protein, Rat Control Peptide (HLA-H) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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