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| Product Name | Inducible Nitric Oxide Synthase, Recombinant, Mouse, His-Tag (iNOS-II/i-NOS) |
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| Description | Highly Purified (~95%). Nitric oxide (NO), a diffusible free radical gas, acts as a neurotransmitter in brain and peripheral nervous system. It accounts for the activity of endothelium-derived relaxing factors, which stimulate vasodilatation by releasing NO from the endothelium. NO is synthesized by L-arginine, oxygen, and NADPH by three known isoforms of heme-containing flavoproteins termed NO synthase (NOS, I-III, mol wt. ~130-160kD). One group of enzyme is constitutive, agonist-triggered, and dependent on Ca2+/Calmodulin and is inhibited by L- arginine analogues (L-NNA, L-NMMA). It is found in endothelium, adrenal glands, brain and platelets. The other principle group is inducible, Ca2+/Calmodulin-independent, and inhibited by NMMA and L-NNA. It has been found in macrophage, hepatocytes, tumor cells, vascular smooth muscle and endothelial cells. Analyses of cDNA clones have identified three distinct NOS genes in mammals: neuronal (nNOS/bNOS/NOS-I), endothelial (eNOS/NOS-III), and ma |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: BC062378 |
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| Catalog # | 209024 |
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| Order / More Info | Inducible Nitric Oxide Synthase, Recombinant, Mouse, His-Tag (iNOS-II/i-NOS) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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