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| Product Name | PNKP, Recombinant, Human, aa1-521, His-SUMO-Tag (Bifunctional Polynucleotide Phosphatase/Kinase) |
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| Description | Purity ~90% (SDS-PAGE). Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone. Source: Recombinant protein corresponding to aa1-521 from human PNKP, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~73.1kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | DNA 5'-kinase/3'-phosphatase, Polynucleotide kinase-3'-phosphatase 2 domains,Polynucleotide 3'-phosphatase (EC:3.1.3.32), 2'(3')-polynucleotidase Polynucleotide 5'-hydroxyl-kinase (EC:2.7.1.78) |
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| Gene, Accession, CAS # | SwissProt: Q96T60 |
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| Catalog # | 374771 |
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| Order / More Info | PNKP, Recombinant, Human, aa1-521, His-SUMO-Tag (Bifunctional Polynucleotide Phosphatase/Kinase) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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