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| Product Name | WIN 18,446 |
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| Description | Purity >98%. WIN 18,446 is a bis -(dichloroacetyl)-diamine which inhibits aldehyde dehydrogenase 1a2, (IC50 = 300 nM), a testes-specific isoform of the enzyme involved in vitamin A metabolism. In this way, WIN 18,446 suppresses the expression of several genes that are regulated by retinoic acid and are necessary for spermatogenesis. As a result, WIN 18,446 may cause infertility in males. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N,N'-1,8-octanediylbis[2,2-dichloro-acetamide], NSC 59354 |
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| Gene, Accession, CAS # | CAS: 1477-57-2 |
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| Catalog # | LS-H10488 |
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| Price | |
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| Order / More Info | WIN 18,446 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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