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| Product Name | Recombinant Shigella flexneri serotype X E3 ubiquitin-protein ligase ipaH9.8 |
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| Description | 1-545aa; Full Length. MW: 66.1kD. Purity >90% as determined by SDS-PAGE. Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway and modulates the acute inflammatory responses, thus facilitating bacterial colonization within the host cell. Interacts with IKBKG (NO) and TNIP1 (ABIN-1), a ubiquitin-binding adapter protein, which results in TNIP1-dependent 'Lys- |
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| Size | 0.01 mg (Yeast), 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.1 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Invasion plasmid antigen ipa; H9.8] |
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| Gene, Accession, CAS # | ipaH9.8, Gene ID: 1238048, Accession: NP_858359.2 |
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| Catalog # | MBS1056130 |
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| Order / More Info | Recombinant Shigella flexneri serotype X E3 ubiquitin-protein ligase ipaH9.8 from MYBIOSOURCE INC. |
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| Product Specific References | Induction of type III secretion in Shigella flexneri is associated with differential control of transcription of genes encoding secreted proteins.Demers B., Sansonetti P.J., Parsot C.EMBO J. 17:2894-2903(1998) The virulence plasmid pWR100 and the repertoire of proteins secreted by the type III secretion apparatus of Shigella flexneri.Buchrieser C., Glaser P., Rusniok C., Nedjari H., d'Hauteville H., Kunst F., Sansonetti P.J., Parsot C.Mol. Microbiol. 38:760-771(2000) Complete DNA sequence and an |
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