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| Product Name | GX15-070 |
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| Description | Purity >98%. Cell-permeable. A small molecule pan-Bcl-2 antagonist that mimics BH3-only proteins by binding to multiple antiapoptotic Bcl-2 members. GX15-070 has been shown to overcome Bcl-2-, Bcl-xl-, Bcl-w-, and Mcl-1-mediated resistance to Bax or Bak. It potently interferes with the direct interaction between Mcl-1 and Bak in intact outer mitochondrial membrane and inhibits the association between Mcl-1 and Bak in intact cells. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (Z)-2-(2-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)-3-methoxy-2H-pyrrol-5-yl)-1H-indole methanesulfonate |
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| Gene, Accession, CAS # | CAS: 803712-67-6 |
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| Catalog # | LS-H2661 |
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| Order / More Info | GX15-070 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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