| 产品详情 |
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| Product Name | Eeyarestatin I |
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| Description | MW: 630.44. Purity ≥98% by HPLC. Eeyarestatin I is an inhibitor of the ERAD (Endoplasmic-reticulum-associated protein degradation) pathway; blocking the degradation of misfolded proteins at a dose of 8 uM. It associates with the p97-associated deubiquitinating complex in cells; preventing deubiquitination of substrates by ataxin-3 (atx3). Also inhibits Sec61-mediated protein translocation at the ER. Displays cytotoxic activity preferentially against cancer cells; induces cell death via the pr |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [3- (4-Chlorophenyl)-4-[[[ (4-chlorophenyl) amino]carbonyl]hydroxyamino]-5; 5-dimethyl-2-oxo-1-imidazolidineacetic acid 2-[3- (5-nitro-2-furanyl)-2-propen-1-ylidene]hydrazide] |
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| Gene, Accession, CAS # | CAS: 412960-54-4 |
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| Catalog # | MBS845782 |
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| Price | |
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| Order / More Info | Eeyarestatin I from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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