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| Product Name | 14,15-EE-5(Z)-E |
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| Description | Purity >98%. Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity. 14,15-EE-5(Z)-E is a structural analog of 14,15-epoxyeicosatrienoic acids (14,15-EET) that antagonizes EET-induced relaxation of vascular smooth muscle. Relaxation of U46619-constricted bovine arteries by 14,15-EET could be inhibited approximately 80% by 14,15-EE-5(Z)-E at a concentration of 10 µM. 14,15-EE-5(Z)-E does not appear to antagonize nitric oxide- or iloprost-mediated vascular relaxation. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 13-[(2R,3S)-3-pentyloxiranyl]-5Z-tridecenoic acid, 14,15-Epoxyeicosa-5(Z)-enoic Acid |
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| Gene, Accession, CAS # | CAS: 519038-92-7 |
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| Catalog # | LS-H5833 |
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| Price | |
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| Order / More Info | 14,15-EE-5(Z)-E from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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