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| Product Name | Recombinant Human Egl nine homolog 2 |
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| Description | 283-407aa; Partial. MW: 18.2kD. Purity >90% as determined by SDS-PAGE. Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF2A. Hydroxylated HIFs are then |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.05 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Estrogen-induced tag 6; HPH-3; Hypoxia-inducible factor prolyl hydroxylase 1; HIF-PH1; HIF-prolyl hydroxylase 1; HPH-1; Prolyl hydroxylase domain-containing protein 1; PHD1] |
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| Gene, Accession, CAS # | EGLN2, Gene ID: 112398, Accession: NP_444274.1 |
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| Catalog # | MBS1265351 |
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| Order / More Info | Recombinant Human Egl nine homolog 2 from MYBIOSOURCE INC. |
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| Product Specific References | Characterization and comparative analysis of the EGLN gene family.Taylor M.S.Gene 275:125-132(2001) Novel estrogen and tamoxifen induced genes identified by SAGE (Serial Analysis of Gene Expression).Seth P., Krop I., Porter D., Polyak K.Oncogene 21:836-843(2002) Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi |
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