| 产品详情 |
| Edit |   |
|---|
| Product Name | RK-33 |
|---|
| Description | MW: 428.45. Purity ≥98% by HPLC. RK-33 is an inhibitor of DEAD box 3 (DDX3); an ATP-dependent RNA helicase. RK-33 inhibits the growth of lung cancer cells that overexpress DDX3 (IC50s = 4.4-8.4 uM) but is less effective in cells with low DDX3 expression (IC50 > 25 uM). It also promotes radiation sensitization in cells overexpressing DDX3. RK-33 in combination with radiation induces tumor regression in multiple animal models of lung cancer. |
|---|
| Size | 5 mg, 25 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | [3; 7-dihydro-3; 7-bis[ (4-methoxyphenyl) methyl]-2H-diimidazo[4; 5-d:4'; 5'-f][1; 3]diazepin-2-one] |
|---|
| Gene, Accession, CAS # | CAS: 1070773-09-9 |
|---|
| Catalog # | MBS846413 |
|---|
| Price | |
|---|
| Order / More Info | RK-33 from MYBIOSOURCE INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|