| 产品详情 |
| Edit |   |
|---|
| Product Name | Calcineurin Autoinhibitory Peptide |
|---|
| Description | Purity >95% by HPLC. This peptide is a specific inhibitor for calcineurin (PP2BA), a Ser/Thr protein phosphatase from the PPP family and PP2B subfamily. The peptide corresponds to the residues 467-491 within the inhibitory domain of human calcineurin alpha subunit. Calcineurin is known to dephosphorylate heat shock protein beta-1 (HSPB1) and protein phosphatase Slingshot homolog 1 (SSH1). This peptide inhibits Mn2+-stimulated calcineurin activity (IC50 = 10 uM using 32P-myosin light chain as substrate) but has no effect on Ni2+-stimulated enzyme activity. It does not inhibit CaMKII kinase, protein phosphatase 1 or 2A. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | Serine/Threonine-protein phosphatase 2B catalytic subunit alpha isoform, Calmodulin-dependent calcineurin A subunit alpha isoform, CAM-PRP catalytic subunit, PPP3CA, CALNA, CAN |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | LS-H5318 |
|---|
| Price | |
|---|
| Order / More Info | Calcineurin Autoinhibitory Peptide from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|