| 产品详情 |
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| Product Name | Recombinant Human Thiopurine S-methyltransferase (TPMT) |
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| Description | 1-245\naa, Full length protein. MW: 28,180 Da. Purity >85% (SDS-PAGE). This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located o |
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| Size | 0.05 mg (E-Coli), 0.2 mg (E-Coli), 0.05 mg (Baculovirus), 0.5 mg (E-Coli), 0.2 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [thiopurine S-methyltransferase isoform 1; Thiopurine S-methyltransferase; thiopurine S-methyltransferase; thiopurine S-methyltransferase; Thiopurine methyltransferase] |
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| Gene, Accession, CAS # | TPMT, Gene ID: 7172, Accession: NP_000358.1 |
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| Catalog # | MBS962512 |
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| Price | |
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| Order / More Info | Recombinant Human Thiopurine S-methyltransferase (TPMT) from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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