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| Product Name | Recombinant Human T-cell immunoreceptor with Ig and ITIM domains |
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| Description | 22-141aa; Extracellular Domain. MW: 18,432 Da. Purity >90% as determined by SDS-PAGE. Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. |
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| Size | 0.05 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli), 1 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain-containing protein 3] |
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| Gene, Accession, CAS # | TIGIT, Gene ID: 201633, Accession: NP_776160.2 |
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| Catalog # | MBS1444441 |
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| Order / More Info | Recombinant Human T-cell immunoreceptor with Ig and ITIM domains from MYBIOSOURCE INC. |
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| Product Specific References | The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.Yu X., Harden K., Gonzalez L.C., Francesco M., Chiang E., Irving B., Tom I., Ivelja S., Refino C.J., Clark H., Eaton D., Grogan J.L.Nat. Immunol. 10:48-57(2009) |
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