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| Product Name | Nafamostat (mesylate) |
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| Description | Purity >98%. Nafamostat is a serine protease inhibitor that is capable of inhibiting trypsin (a digestive system protease; Ki = 15 nM), tryptase (a mast cell protease; Ki = 95.3 pM), and additional proteases in the coagulation cascade including thrombin (Ki = 0.84 µM). In a mouse model of allergic asthma, a dose of 300 mg/kg nafamostat mesylate has been shown to inhibit serine proteolytic activity, to decrease circulating levels of eosinophils and lymphocytes in bronchoalveolar lavage fluid, and to reduce interleukin-13 and eotaxin production associated with antigen-induced airway eosinophilia and goblet cell hyperplasia. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[(aminoiminomethyl)amino]-6-(aminoiminomethyl)-2-naphthalenyl ester-benzoic acid, dimethanesulfonate, Coahibitor, FUT 175, Nafamastat |
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| Gene, Accession, CAS # | CAS: 82956-11-4 |
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| Catalog # | LS-H8906 |
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| Order / More Info | Nafamostat (mesylate) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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