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| Product Name | C2, GST-Tag, Recombinant (CO2, DKFZp779M0311, Complement C2) |
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| Description | Lysate. Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined. Source: Partial length protein corresponding to of C2, fused to GST-Tag at N-terminal, expressed in E. coli. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the |
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| Size | 200ug |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | C2, Gene ID: 717, Accession: NP_000054, SwissProt: P06681 |
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| Catalog # | 500628 |
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| Order / More Info | C2, GST-Tag, Recombinant (CO2, DKFZp779M0311, Complement C2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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