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| Product Name | TL-1A, Recombinant, Human (TNFSF15, VEGI) |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. TL-1A belongs to the TNF superfamily of ligands.It is expressed predominantly in endothelial cells, and to a lesser extent in placenta, lung, kidney, skeletal muscle, pancreas, small intestine and colon.TL-1A inhibits endothelial cell proliferation and angiogenesis, and has been shown to induce NFkB activation, caspase activity, and apoptosis in responding cell lines.TL-1A interacts with TNFRSF25/DR3 receptor, but can also bind to a decoy receptor TNFRSF21/DR6.Recombinant human TL-1A is a 22.0kD polypeptide of 194 amino acid residues. Biological Activity: Determined by its ability to stimulate IFN-gamma; production by human PBMC using a concentration range of 10.0-100.0ng/ml. Note: Results may vary with PBMC donors. AA Sequence: QLRAQGEASVQFQALKGQEFAPSHQQVYAPLRADGDKPRAHLTVVRQTPTQHFKNQFPALHWEHELGLAFTKNRMNYTNKFLLIPESGDYFIYSQVTFRGMTSECSEIRQAGRPNKPDSITVVITKVTDSYPEPTQLLMGTKSVCEVGSNWFQPIYLGAMFSLQEGDKLMVNVSDISLVDYTKEDKTFFGAFLL Quality Control: Ve |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143525 |
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| Order / More Info | TL-1A, Recombinant, Human (TNFSF15, VEGI) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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