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| Product Name | PP3 |
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| Description | Purity >98%. The Src family of non-receptor tyrosine kinases regulate cell adhesion, growth, and differentiation through activation of multiple intracellular signaling pathways. Normally inactive, Src kinases are transiently activated during mitosis and constitutively activated by abnormal mutations. Several small molecule inhibitors of this signaling pathway have been developed as a therapeuptic strategy to abate abnormal Src kinase activity. PP3 is an inactive analog of the Src tyrosine kinase inhibitors PP1 and PP2 . At concentrations as high as 10 µM, it does not prevent proliferation mediated by a stem cell factor/mast cell growth factor in hematopoietic and cancer cell lines. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine, NSC 1401 |
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| Gene, Accession, CAS # | CAS: 5334-30-5 |
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| Catalog # | LS-H9482 |
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| Price | |
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| Order / More Info | PP3 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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