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| Product Name | EX 527 (Selisistat, EX527, SIRT1 Inhibitor III) |
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| Description | Highly Purified (~98%). Synonyms: 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide, Selisistat, EX527, SIRT1 Inhibitor III Chemical Name: 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide Molecular Formula: C13 H13 ClN 2 Molecular Weight: 248.7 CAS Number: 49843-98-3 Purity: ≥98% Applications: FA Appearance: Crystalline solid Description: EX 527 is a selective inhibitor of NAD-dependent deacetylase sirtuin-1 (SIRT1) to the exclusion of histone deacetylases (HDACs) and other sirtuins. It is reported that inhibiting SIRT1 is associated with increasing insulin sensitivity and effecting other metabolic regulatory functions. EX 527 was used to determine that the inactivation of SirT1 stimulates tumor cell proliferation. Storage: Soluble in organic solvents such as ethanol and DMSO. DMSO up to 75mM |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide |
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| Gene, Accession, CAS # | CAS: 49843-98-3 |
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| Catalog # | 366881 |
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| Order / More Info | EX 527 (Selisistat, EX527, SIRT1 Inhibitor III) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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