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| Product Name | ALKBH3, Recombinant, Human, aa1-170, His-SUMO-Tag (Alpha-ketoglutarate-dependent Dioxygenase alkB Homolog 3) |
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| Description | Purity ~90% (SDS-PAGE). Dioxygenase that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative dethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Source: Recombinant protein corresponding to aa1-170 from human ALKBH3, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~35.3kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Alkylated DNA repair protein alkB homolog 3 DEPC-1, Prostate cancer antigen 1 |
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| Gene, Accession, CAS # | SwissProt: Q96Q83 |
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| Catalog # | 372230 |
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| Order / More Info | ALKBH3, Recombinant, Human, aa1-170, His-SUMO-Tag (Alpha-ketoglutarate-dependent Dioxygenase alkB Homolog 3) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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