| 产品详情 |
| Edit |   |
|---|
| Product Name | NR1H3, Recombinant, Human, aa1-402, His-SUMO-Tag (Oxysterols Receptor LXR-alpha) |
|---|
| Description | Purity ~90% (SDS-PAGE). Nuclear receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism. Source: Recombinant protein corresponding to aa1-402 from human NR1H3, fused to His-SUMO-Tag at N-terminal expressed in E. coli. Molecular Weight: ~61.7kD AA |
|---|
| Size | 10ug, 50ug, 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | Liver X receptor alphaNuclear receptor subfamily 1 group H member 3 |
|---|
| Gene, Accession, CAS # | SwissProt: Q13133 |
|---|
| Catalog # | 374464 |
|---|
| Price | |
|---|
| Order / More Info | NR1H3, Recombinant, Human, aa1-402, His-SUMO-Tag (Oxysterols Receptor LXR-alpha) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|