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| Product Name | Urokinase Plasminogen Activator Receptor ELISA Kit, BioAssay™ (uPAR) |
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| Description | Urokinase-type plasminogen activator receptor (uPAR, CD87) is a cell surface receptor that binds urokinase-type plasminogen activator (uPA) with high affinity, thereby facilitating the pericellular activation of plasminogen (see references 1 and 2 for reviews). uPAR, uPA and plasminogen activator inhibitor-1 (PAI-1), form a triad with multiple functions, including regulation of cell attachment, migration, proliferation and differentiation, by both proteolytic and nonproteolytic mechanisms (2). uPAR is anchored to extracellular surfaces through a glycosyl phosphatidylinositol (GPI) linkage, with no transmembrane domain (3). uPAR is synthesized as a 335-amino-acid polypeptide that includes a 22-residue signal peptide (4). A 30-residue peptide is cleaved from the C-terminus during addition of the GPI anchor (3). With loss of the signal peptide and the C-terminal peptide, the mature protein has 283 amino acids. It is variably glycosylated, increasing its mass from about 31kD for the protei |
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| Size | 1 kit |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | U2610-07 |
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| Order / More Info | Urokinase Plasminogen Activator Receptor ELISA Kit, BioAssay™ (uPAR) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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