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| Product Name | Urokinase Plasminogen Activator Receptor Recombinant, Human (uPAR, CD87) |
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| Description | Purity > 95%, as determined by SDS-PAGE and visualized by silver stain. Human uPAR. The urokinase-type plasminogen activator (uPA) is one of two activators that converts the extracellular zymogen plasminogen to plasmin, a serine protease that is involved in a variety of normal and pathological processes that require cell migration and/or tissue destruction. uPA is synthesized and released from cells as a single-chain (sc) pro-enzyme with limited enzymatic activity and is converted to an active two-chain (tc) disulfide-linked active enzyme by plasmin and other specific proteinases. Both the scuPA and tcuPA bind with high-affinity to the cell surface via the glycosyl phosphatidylinositol-linked receptor uPAR which serves to localize the uPA proteolytic activity. The enzymatic activity of scuPA has also been shown to be enhanced by binding to uPAR. Independent of their proteolytic activity, the uPA/uPAR interaction also initiates signal transduction responses resulting in activation of p |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q03405 |
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| Catalog # | U2610-04A |
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| Order / More Info | Urokinase Plasminogen Activator Receptor Recombinant, Human (uPAR, CD87) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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