| 产品详情 |
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| Antigenic Specificity | TREM1 |
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| Clone | L5-B8.2A12.3A12 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a |
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| Format | Protein G purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | Flo (1:25 - 1:100), IF, IHC, IHC-Fr, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TREM1 Antibody (clone L5-B8.2A12.3A12) LS-C188343. Recognizes mouse triggering receptor expressed on myeloid cells 1 (TREM-1), a 30kD member of the immunoglobulin superfamily expressed on neutrophils and a subset of monocytes. TREM-1 is involved in the microbial inflammatory response. It acts in conjunction with the adaptor protein DAP12 to activate neutrophils and monocytes, leading to the secretion of pro-inflammatory mediators and enhancement of the inflammatory response. Microbial infection also induces the release of soluble form of TREM-1 from monocytes, which is reported to act as an inhibitor of TREM-1. TREM-1 mediates the septic shock pathway, and blocking TREM-1 has been reported to reduce inflammation and increase survival in certain models of bacterial infection. |
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| Immunogen | Mouse TREM-1 Fc fusion protein. |
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| Other Names | TREM1, CD354, CD354 antigen, Triggering-receptor TREM1, TREM-1 |
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| Gene, Accession # | TREM1, Gene ID: 54210 |
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| Catalog # | LS-C188343 |
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| Price | |
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| Order / More Info | TREM1 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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