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| Product Name | Prealbumin, Human, Positive Control for Western Blot (Transeryhtin, TTR) |
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| Description | Transthyretin (TTR) is a serum and cerebrospinal fluid carrier of the thyroid hormone thyroxine (T4) and retinol binding protein bound to retinol. This is how transthyretin gained its name, transports thyroxine and retinol. The liver secretes transthyretin into the blood, and the choroid plexus secretes TTR into the cerebrospinal fluid. TTR was originally called prealbumin[1] because it ran faster than albumin on electrophoresis gels. It functions in concert with two other thyroid hormone-binding proteins (Albumin and TBG) in the serum. In cerebrospinal fluid TTR is the primary carrier of T4, as albumin is not present. TTR also acts as a carrier of retinol (vitamin A) through its association with retinol-binding protein (RBP) in the blood and the CSF. Less than 1% of TTR's T4 binding sites are occupied in blood, which is taken advantage of below to prevent TTRs dissociation, misfolding and aggregation which leads to the degeneration of post-mitotic tissue. TTR is a 55kD homotetramer wi |
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| Size | 100ul |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 209151 |
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| Order / More Info | Prealbumin, Human, Positive Control for Western Blot (Transeryhtin, TTR) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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