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| Product Name | DHRS2, Recombinant, Human, aa1-300, GST-Tag (Dehydrogenase/Reductase SDR Family Member 2) |
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| Description | Purity ~90% (SDS-PAGE). Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21. Source: Recombinant protein corresponding to aa1-300 from human DHRS2, fused to GST-Tag at N-terminal expressed in E. coli. Molecular Weight: ~58.5kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Dicarbonyl reductase HEP27 Protein D, dehydrogenase/reductase family 25C member 1 |
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| Gene, Accession, CAS # | SwissProt: Q13268 |
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| Catalog # | 373052 |
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| Order / More Info | DHRS2, Recombinant, Human, aa1-300, GST-Tag (Dehydrogenase/Reductase SDR Family Member 2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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