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| Product Name | FKBP1a /FKBP12, 1-108aa, Recombinant, Human |
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| Description | Purified. ≥95% by SDS-PAGE. FK506 binding protein 1a, also known as FKBP12, belongs to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP12 also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes, cardiac and skeletal ryanodine receptors and the inositol 1,4,5-trisphosphate receptor. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. Recombinant human FKBP12, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. Molecular Weight: 14.1kD (128aa) Endotoxin Level: ≤1.0 EU per 1 ug of protein (determined by LAL method). AA Sequence: MGSSHHHHHH SSGLVPRGSH MGVQVETISP GDGRTFPKRG QTCVVHYTGM LEDGKKFDSS RDRNKPFKFM LGKQEVIRGW EEGVAQMSVG QRAKLTISPD YAYGATGHPG IIPPHATLVF DVELLKLE Enzyme Activity: Specific activity is > 800 nmol/min |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | FKBP1a /FKBP12, 1-108aa, Recombinant, Human (FK506 binding protein 1a, 12kD, PPIase FKBP1A, Rotamase, FKBP1, PKC12) |
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| Gene, Accession, CAS # | Accession: NP_463460 |
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| Catalog # | F4150-30A |
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| Order / More Info | FKBP1a /FKBP12, 1-108aa, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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