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| Product Name | FKBP1a, Recombinant, Human, aa1-108, His-Tag |
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| Description | Purity ~95% (SDS-PAGE). FKBP1A is part of the family of immunophilins, which have in common high affinity for immunosuppressant drugs and a peptidyl-prolyl cis-trans isomerase (PPIase). In the absence of immunosuppressive ligands, FKBP1A is involved in intracellular calcium regulation by associating with 3 types of Ca2+ release channel complexes: skeletal ryanodine receptors, cardiac ryanodine receptors and the inositol 1, 4, 5-triphosphate receptor. FKBP1A also interacts with TGF type I receptor exerting an inhibitory effect on the TGFbeta-I signaling pathway. FKBP12 plays a role in modulation of ryanodine receptor isoform-1 (ryr-1), a component of the calcium release channel of skeletal muscle sarcoplasmic reticulum. FKBP1A increase the folding of proteins and catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Source: Recombinant protein corresponding to aa1-108 from human FKBP1A, fused to His-tag at N-terminus, expressed in E. coli. Molecular Wei |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | FKBP1a, Recombinant, Human, aa1-108, His-Tag (FKBP12, FK506 binding protein 1a, 12kD, PPIase FKBP1A, Rotamase, FKBP1, PKC12) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 169965 |
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| Order / More Info | FKBP1a, Recombinant, Human, aa1-108, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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