| 产品详情 |
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| Product Name | Recombinant Human herpesvirus 1 ICP47 protein |
| Description | 1-88aa; full length protein. MW: 11.79kD. Purity >90% as determined by SDS-PAGE. Plays a role in the inhibition of host immune response. Binds specifically to transporters associated with antigen processing (TAP), thereby blocking peptide-binding and translocation by TAP as well as subsequent loading of peptides onto MHC class I molecules. pty MHC I molecules are retained in the endoplasmic reticulum and ultimately directed to proteasomal degradation. In consequence, infected cells are masked fo |
| Size | 0.01 mg (Yeast), 0.05 mg (Yeast), 0.1 mg (Yeast), 0.2 mg (Yeast), 0.05 mg (E-Coli) |
| Concentration | n/a |
| Applications | n/a |
| Other Names | [Immediate-early protein IE12; Immediate-early-5; Infected cell protein 47; US12 protein; Vmw12 ] |
| Gene, Accession, CAS # | US12, Gene ID: 2703441, Accession: YP_009137148.1 |
| Catalog # | MBS1252493 |
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| Order / More Info | Recombinant Human herpesvirus 1 ICP47 protein from MYBIOSOURCE INC. |
| Product Specific References | DNA sequence of an immediate-early gene (IEmRNA-5) of herpes simplex virus type I.Watson R.J., Vande Woude G.F.Nucleic Acids Res. 10:979-991(1982) DNA sequence analysis of an immediate-early gene region of the herpes simplex virus type 1 genome (map coordinates 0.950 to 0.978).Murchie M.-J., McGeoch D.J.J. Gen. Virol. 62:1-15(1982) A 3' co-terminal family of mRNAs from the herpes simplex virus type 1 short regiontwo overlapping reading frames encode unrelated polypeptide one of which has highly |
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