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| Product Name | PRKAB2, Recombinant, Human, aa1-272, GST-Tag (5'-AMP-Activated Protein Kinase Subunit beta-2) |
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| Description | Purity ~90% (SDS-PAGE). Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3). Source: Recombinant protein corresponding to aa1-272 from human PRKAB2, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~57.3kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: O43741 |
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| Catalog # | 374849 |
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| Order / More Info | PRKAB2, Recombinant, Human, aa1-272, GST-Tag (5'-AMP-Activated Protein Kinase Subunit beta-2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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