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| Product Name | PRKAB1, Recombinant, Human, aa1-270, His-Tag |
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| Description | Purity ~85% (SDS-PAGE). 5'-AMP-activated protein kinase subunit beta-1, also known as PRKAB1, inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3). Source: Recombinant protein corresponding to aa1-270 from human PRKAB1 at N-terminal, fused to His-tag expressed in E.coli. Molecular Weight: ~32.8kD (293aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMGNTSSE RAALERHGGH KTPRRDSSGG TKDGDRPKIL MDSPEDADLF HSEEIKAPEK EEFLAWQHDL EVNDKAPAQA RPTVFRWTGG GKEVYLSGSF NNWSKLPLTR SHNNFVAILD LPEGEHQYKF FVDGQWTHDP SEPIVTSQLG TVN |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PRKAB1, Recombinant, Human, aa1-270, His-Tag (5'-AMP-activated Protein Kinase Subunit Beta-1, AMPK, HAMPKb) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 138718 |
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| Order / More Info | PRKAB1, Recombinant, Human, aa1-270, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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