| 产品详情 |
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| Product Name | c-Jun Control Cell Extracts |
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| Description | C-Jun is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73 (1,2). Extracellular signals including growth factors, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. Mutation of Ser63/73 renders c-Jun nonresponsive to mitogenic and stress induced signaling pathways. The MAP kinase homologue, SAPK/JNK, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. In addition, the activity of SAPK/JNK is stimulated by the same signals that activate c-Jun (3,4). Nonphosphorylated c-Jun (Ser63) II Cell Extracts: Total cell extracts from NIH/3T3 cells, prepared without treatment, serve as a negative control. Kit Compontents: C5815-08A Non-phosphorylated c-Jun control extract. 1x150ul Supplied as a liquid in 62.5 mM Tris-HCl, pH 6.8, 2% SDS, 10% glyce |
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| Size | 10Blots |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C5815-08 |
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| Order / More Info | c-Jun Control Cell Extracts from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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